CPN Pre-Clinical, Correlative, and Translational Research

In Development

CPN1742 Differential gene expression signature as a predictive biomarker of an immune response to a preventative cancer vaccine Dr. Olivera Finn, University of Pittsburgh

Active

CPN1128 Plasma and Sputum microRNAs: Utility as Noninvasive Biomarkers for the Progression/Regression of Bronchial Dysplasia Dr. Fekadu Kassie, University of Minnesota
CPN1641 Chemoprevention in Barrett's Esophagus Drs. Zigang Dong and Tianshun Zhang, Hormel Institute
CPN1741 T-Cell Receptor (TCR) Repertoire Pre- and Post-MUC1 Vaccine Drs. Olivera Finn and John McKolanis, University of Pittsburgh

Completed

CPN0935 Feasibility Study to Assess Interest for Chemoprevention Trial Participation Among BRCA Mutation Carriers Dr. Sandhya Pruthi, Mayo Clinic
CPN0942 Pilot Study of MHC Class I Protein Expresson in FAP-Associated Dysplastic and Histologically-Normal Gastrointestinal Tissue Specimens Drs. Paul Limburg and Thomas Smyrk, Mayo Clinic
CPN1033 BRCA Gene Mutation Carrier Versus Normal Breast Tissue: Biomarkers of Breast Cancer Risk Drs. Sandhya Pruthi, Mayo Clinic, and Dr. Patricia Thompson, University of Arizona
CPN1191 Population-Based Pharmacokinetic Analyses of data from the Bioequivalency Study of Sulindac in Capsule vs. Tablet Formulations Drs. Joel Reid and Alexander Berg, Mayo Clinic
CPN1341 15-Prostaglandin Dehydrogenase Expression in Barrett’s Esophagus as a Correlate of Response to Aspirin Therapy Dr. Linda Cummings, University Hospitals/Case Medical Center
CPN1342 Methylated NTRK3 and Colorectal Cancer Formation Dr. William Grady, Fred Hutchinson Cancer Center
CPN1441 The Role of Gastrin in Proliferation and Apoptosis in Nondysplastic Human Barrett's Esophagus Dr. Navtej Buttar, Mayo Clinic
CPN1442 Metformin and mitochondrial homeostasis in Barrett’s esophagus Dr. Hiroski Nakagawa, University of Pennsylvania
CPN1443 Identification of Differentially Expressed Genes in Barrett's Esophagus With and Without Metformin Drs. Navtej Buttar, Mayo Clinic, and Amitabh Chak, University Hospitals/Case Medical Center
CPN1444 CDX2 Levels in Patients after Endoscopic Radiofrequency Ablation with Gaviscon Drs. Navteh Buttar, Mayo Clinic, and Chin Hur, Massachusetts General Hospital
CPN1521 Preliminary test for abnormal expression of cyclin B1 and MUC1 on bronchial dysplasia Dr. Olivera Finn, University of Pittsburgh
CPN1621 pAKT Signaling Affected by Myo-inositol versus Placebo in Smokers with Bronchial Dysplasia Dr. Stephen Lam, British Columbia Cancer Agency